Question 1:
A. in charge of
B. in opposition to
C. in search of
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in charge of: responsible for something or someone

in opposition to: in contrast or conflict

in search of: look for 

in lieu of: instead of

=>  "in search of" has the most appropriate meaning

D. in lieu of

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TEST 12- minitest - Practice Toeic | Englishfreetest.com